Original paper
Quantitative Modeling of Nucleosome Unwrapping from Both Ends
Abstract
In eukaryotic cells, DNA is packaged into chromatin where nucleosomes are the basic packaging unit. Important cellular processes including gene expression, DNA replication, and DNA repair require nucleosomal DNA to be unwrapped so that functional proteins can access their target sites, which otherwise are sterically occluded. A key question in this process is what the unwrapped conformations individual nucleosomes adopt within chromatin are....
Paper Details
Title
Quantitative Modeling of Nucleosome Unwrapping from Both Ends
Published Date
Dec 1, 2019
Journal
Volume
117
Issue
11
Pages
2204 - 2216
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Notes
History