Zebrafishdscaml1Deficiency Impairs Retinal Patterning and Oculomotor Function
Abstract
Down syndrome cell adhesion molecules (dscam and dscaml1) are essential regulators of neural circuit assembly, but their roles in vertebrate neural circuit function are still mostly unexplored. We investigated the functional consequences of dscaml1 deficiency in the larval zebrafish (sexually undifferentiated) oculomotor system, where behavior, circuit function, and neuronal activity can be precisely quantified. Genetic perturbation of dscaml1...
Paper Details
Title
Zebrafishdscaml1Deficiency Impairs Retinal Patterning and Oculomotor Function
Published Date
Nov 4, 2019
Journal
Volume
40
Issue
1
Pages
143 - 158
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