The use of human papillomavirus DNA methylation in cervical intraepithelial neoplasia: A systematic review and meta-analysis
Abstract
Methylation of viral DNA has been proposed as a novel biomarker for triage of human papillomavirus (HPV) positive women at screening. This systematic review and meta-analysis aims to assess how methylation levels change with disease severity and to determine diagnostic test accuracy (DTA) in detecting high-grade cervical intra-epithelial neoplasia (CIN).We performed searches in MEDLINE, EMBASE and CENTRAL from inception to October 2019. Studies...
Paper Details
Title
The use of human papillomavirus DNA methylation in cervical intraepithelial neoplasia: A systematic review and meta-analysis
Published Date
Dec 1, 2019
Journal
Volume
50
Pages
246 - 259
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