Adipose tissue NAD + biosynthesis is required for regulating adaptive thermogenesis and whole-body energy homeostasis in mice
Volume: 116, Issue: 47, Pages: 23822 - 23828
Published: Nov 6, 2019
Abstract
Nicotinamide adenine dinucleotide (NAD + ) is a critical coenzyme for cellular energy metabolism. The aim of the present study was to determine the importance of brown and white adipose tissue (BAT and WAT) NAD + metabolism in regulating whole-body thermogenesis and energy metabolism. Accordingly, we generated and analyzed adipocyte-specific nicotinamide phosphoribosyltransferase ( Nampt ) knockout (ANKO) and brown adipocyte-specific Nampt...
Paper Details
Title
Adipose tissue NAD + biosynthesis is required for regulating adaptive thermogenesis and whole-body energy homeostasis in mice
Published Date
Nov 6, 2019
Volume
116
Issue
47
Pages
23822 - 23828
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