Original paper
Off-target effects of cytidine base editor and adenine base editor: What can we do?
Volume: 46, Issue: 11, Pages: 509 - 512
Published: Nov 1, 2019
Abstract
Base editors (BEs) is a powerful tool that could edit the genome efficiently without inducing DNA double-strand breaks (DSBs). Recently, off-target DNA and RNA mutations of BEs were found, rasing concerns about its precision and safety. Here we discuss some strategies that might eliminate off-target effects of...
Paper Details
Title
Off-target effects of cytidine base editor and adenine base editor: What can we do?
Published Date
Nov 1, 2019
Volume
46
Issue
11
Pages
509 - 512
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Notes
History