Original paper

Hmga2 Functions As an Oncogene upon the Deletion of Tet2 and Promotes the Pathogenesis of Myelodysplastic Syndrome

Blood21.00
Volume: 134, Issue: Supplement_1, Pages: 3782 - 3782
Published: Nov 13, 2019
Abstract
High Mobility Group AT-hook 2 (HMGA2) is a chromatin modifier and its overexpression has been found in a subset of patients with myelodysplastic syndrome (MDS). The high level of HMGA2 expression appears to predict poor prognosis in various tumors; however, it remains unclear how HMGA2 dysregulates expression of target genes to facilitate the transformation. To elucidate the mechanisms by which the overexpression of Hmga2 promotes the...
Paper Details
Title
Hmga2 Functions As an Oncogene upon the Deletion of Tet2 and Promotes the Pathogenesis of Myelodysplastic Syndrome
Published Date
Nov 13, 2019
Journal
Volume
134
Issue
Supplement_1
Pages
3782 - 3782
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