Pharmacological and Behavioral Effects of the Synthetic Cannabinoid AKB48 in Rats

Sabrine Bilel; Micaela Tirri; Raffaella Arfè; Serena Stopponi; Laura Soverchia; Roberto Ciccocioppo; Paolo Frisoni; Sabina Strano-Rossi; Cristina Miliano; Fabio De-Giorgio; Matteo Marti

doi:https://doi.org/10.3389/fnins.2019.01163

doi.org/10.3389/fnins.2019.01163

Pharmacological and Behavioral Effects of the Synthetic Cannabinoid AKB48 in Rats

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..., Matteo Marti

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Frontiers in Neuroscience4.30

Volume: 13

Published: Oct 30, 2019

Abstract

AKB48 is a designer drug belonging to the indazole synthetic cannabinoids class, illegally sold as herbal blend, incense, or research chemicals for their psychoactive cannabis-like effects. In the present study, we investigated the in vivo pharmacological and behavioral effects of AKB48 in male rats and measured the pharmacodynamic effects of AKB48 and simultaneously determined its plasma pharmacokinetic. AKB48 at low doses preferentially...

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Paper Details

Title

Pharmacological and Behavioral Effects of the Synthetic Cannabinoid AKB48 in Rats

DOI

doi.org/10.3389/fnins.2019.01163

Published Date

Oct 30, 2019

Journal

Frontiers in Neuroscience

Volume

13

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