Herding behavior refers to the social phenomenon in which people are intensely influenced by decisions and behaviors of others in the same group. Even though several recent studies have explored the neural basis of herding decisions in people’s daily life (e.g., consumption decision), the neural processing of herding decisions in enterprise behavior is still unclear. To address this issue, this study extracted the event-related potentials (ERPs) from electroencephalographic data when participant...
Machine learning classification techniques are frequently applied to structural and resting-state fMRI data to identify brain-based biomarkers for developmental disorders. However, task-related fMRI has rarely been used as a diagnostic tool. Here, we used structural MRI, resting-state connectivity and task-based fMRI data to detect congenital amusia, a pitch-specific developmental disorder. All approaches discriminated amusics from controls in meaningful brain networks at similar levels of accur...
Last.Erich Seifritz(UZH: University of Zurich)H-Index: 47
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An important contribution of the thalamus to the transition from wakefulness to sleep is a consistent finding in animal studies. In humans, only little is currently known about the specific role of the thalamus in regulating wake-sleep transitions. Although changes in thalamic blood flow and activity have been reported, the underlying molecular mechanisms have not been investigated. Knowledge about neurotransmitter changes at the wake-to-sleep transition would be indispensable for a better trans...
#1Vaughn R. Steele(NIH: National Institutes of Health)H-Index: 14
#2Andrea M Maxwell(NIDA: National Institute on Drug Abuse)H-Index: 1
Last.Betty Jo Salmeron(NIDA: National Institute on Drug Abuse)H-Index: 24
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There are no effective treatments for cocaine use disorder (CUD), a chronic, relapsing brain disease characterized by dysregulated circuits related to cue reactivity, reward processing, response inhibition, and executive control. Transcranial magnetic stimulation (TMS) has the potential to modulate circuits and networks implicated in neuropsychiatric disorders, including addiction. Although acute applications of TMS have reduced craving in urine-negative cocaine users, the tolerability and safet...
Last.Matteo Marti(University of Ferrara)H-Index: 31
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AKB48 is a synthetic cannabinoid belonging to a structural class with an indazole core structure, illegally marketed as incense, herbal preparations, or research chemicals for their psychoactive cannabis-like effects. In the present study, we investigated the in vivo pharmacological and behavioural effects of AKB48 in male rats and measured the pharmacodynamic effects of AKB48 and simultaneously determined its plasma pharmacokinetic. AKB48 at low doses preferentially stimulated dopamine release ...
The endogenous spinal cord ependymal cells (SCECs), which form the central canal (CC), are critically involved in proliferation, differentiation and migration after spinal cord injury (SCI) and represents a repair cell source in treating SCI. Previously, we reported that BAF45D is expressed in the SCECs and the spinal cord neurons in adult mice and knockdown of BAF45D fail to induce expression of PAX6, a neurogenic fate determinant, during early neural differentiation of human embryonic stem cel...
#2Lauren Hayes(ASU: Arizona State University)H-Index: 4
Cochlear implant (CI) users’ poor speech recognition in noise and music perception may be both due to their limited access to pitch cues such as the fundamental frequency (F0). Recent studies showed that similar to residual low-frequency acoustic hearing, vibrotactile presentation of the F0 significantly improved speech recognition in noise of CI users. The present study tested whether F0-based vibrotactile stimulation can improve melodic contour identification (MCI) of normal-hearing listeners ...