Acquired von Willebrand syndrome in patients on long-term left ventricular assist device support: Results of a Belgian center

Acquired von Willebrand syndrome (aVWS) in patients treated with a left ventricular assist device (LVAD) is characterized by a loss of high molecular weight (HMW) von Willebrand factor (VWF) multimers which often coincides with an impaired VWF function reflected by a decreased VWF collagen-binding capacity and decreased binding of VWF to the platelet glycoprotein (GP) Ib receptor [ [1] Uriel N. Pak S.W. Jorde U.P. Jude B. Susen S. Vincentelli A....