Failed B cell survival factor trials support the importance of memory B cells in multiple sclerosis
Abstract
Clinical trials are probably the most informative experiments to help an understanding of multiple sclerosis (MS) biology. Recent successes with CD20‐depleting antibodies have focused attention towards B cell subsets as important mediators in MS. The trial of tabalumab (NTC00882999), which inhibits B cell activation factor (BAFF), is reported and reviewed and this trial is contrasted with the trial on the inhibition of a proliferation‐inducing...
Paper Details
Title
Failed B cell survival factor trials support the importance of memory B cells in multiple sclerosis
Published Date
Nov 6, 2019
Volume
27
Issue
2
Pages
221 - 228
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