Original paper
PKM2 regulates endothelial cell junction dynamics and angiogenesis via ATP production
Abstract
Angiogenesis, the formation of new blood vessels from pre-existing ones, occurs in pathophysiological contexts such as wound healing, cancer, and chronic inflammatory disease. During sprouting angiogenesis, endothelial tip and stalk cells coordinately remodel their cell-cell junctions to allow collective migration and extension of the sprout while maintaining barrier integrity. All these processes require energy, and the predominant ATP...
Paper Details
Title
PKM2 regulates endothelial cell junction dynamics and angiogenesis via ATP production
Published Date
Oct 21, 2019
Journal
Volume
9
Issue
1
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Notes
History