P4-106: INTEGRATIVE ANALYSIS POINTS TO AGFG2 AS A NOVEL PLAYER IN THE PATHOLOGY OF ALZHEIMER DISEASE

Alzheimer disease (AD) is a complex disorder with diversity in phenotype, onset and progression of clinical symptoms. Ultimately, AD is characterized by the deposition of amyloid beta (Aβ) and phosphorylated tau protein aggregates in the brain. We hypothesize that different clinical AD manifestations may result from common altered pathways relevant to the development of pathology. In our effort to identify novel players to the missing...