Altered RNA Processing in Cancer Pathogenesis and Therapy
Abstract
Major advances in our understanding of cancer pathogenesis and therapy have come from efforts to catalog genomic alterations in cancer. A growing number of large-scale genomic studies have uncovered mutations that drive cancer by perturbing cotranscriptional and post-transcriptional regulation of gene expression. These include alterations that affect each phase of RNA processing, including splicing, transport, editing, and decay of messenger...
Paper Details
Title
Altered RNA Processing in Cancer Pathogenesis and Therapy
Published Date
Nov 1, 2019
Journal
Volume
9
Issue
11
Pages
1493 - 1510
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Notes
History