Abstract 748: Circulating Extracellular Vesicles as Novel Biomarkers of Cardiovascular Risk in Older Women With Different Sitting Time Patterns

Background and Hypothesis: Extracellular vesicles (EVs) are membrane-bound particles shed from a variety of cell types. They contain molecular cargo from the parent cell including metabolites, proteins, and nucleic acids. EVs are present in biofluids and could be promising biomarkers for monitoring wellness. Total sedentary time is linearly associated with cardiovascular and coronary heart disease mortality risk among older women, indicating the...