Derivatization‐free determination of short‐chain volatile amines in human plasma and urine by headspace gas chromatography‐mass spectrometry

Background Short‐chain volatile amines (SCVA) are an interesting compound class playing crucial roles in physiological and toxicological human settings. Dimethylamine (DMA), trimethylamine (TMA), diethylamine (DEA), and triethylamine (TEA) were investigated in detail. Methods Headspace gas chromatography coupled to mass spectrometry (HS‐GC‐MS) was used for the simultaneous qualitative and quantitative determination of four SCVA in different...