Genome-wide linkage analysis of carotid artery traits in exceptionally long-lived families

Background and aims null Atherosclerosis develops with age and is partially controlled by genetics. Research to date has identified common variants with small effects on atherosclerosis related traits. We aimed to use family-based genome-wide linkage analysis to identify chromosomal regions potentially harboring rare variants with larger effects for atherosclerosis related traits. null null null Methods null Participants included 2205...