28.3 PERSON-LEVEL PREDICTION OF PROGRESSION ALONG THE BIPOLAR TRAJECTORY

Bipolar disorder (BD) rarely comes out of the blue; rather, it is generally preceded by subthreshold mood symptoms that may portend a full-threshold bipolar I disorder/bipolar II disorder (BD-I/II), particularly in youth at familial risk. Over the past several years, we and others have used longitudinal data from familial and/or clinical high-risk groups to assess predictors of progression along the trajectory to BD-I/II. These analyses are a...