The Case for Modeling Human Infection in Zebrafish

Mycobacterium marinum infection in zebrafish is an important system for studying natural host–pathogen interactions in vivo.New work has shown that a wide variety of human pathogens can also be studied using a zebrafish infection model.Zebrafish larvae are highly valuable in the discovery and dissection of fundamental concepts underlying human infection.A better understanding of the biology of human pathogens in vivo will be necessary to develop...