Fenofibrate induces PPARα and BMP2 expression to stimulate osteoblast differentiation
Volume: 520, Issue: 2, Pages: 459 - 465
Published: Dec 1, 2019
Abstract
The peroxisome proliferator-activated receptor (PPAR)-α agonist fenofibrate is used as a lipid-lowering agent to reduce cholesterol and triglyceride in blood. In this study, we investigated whether fenofibrate affects osteoblast differentiation of osteogenic precursor cells. Quantitative real-time PCR and alkaline phosphatase (ALP) staining assays revealed that fenofibrate can enhance the osteoblast differentiation of C3H10T1/2 and MC3T3-E1...
Paper Details
Title
Fenofibrate induces PPARα and BMP2 expression to stimulate osteoblast differentiation
Published Date
Dec 1, 2019
Volume
520
Issue
2
Pages
459 - 465
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