Original paper
Astrocyte–microglial association and matrix composition are common events in the natural history of primary familial brain calcification
Abstract
Primary familial brain calcification (PFBC) is an age‐dependent and rare neurodegenerative disorder characterized by microvascular calcium phosphate deposits in the deep brain regions. Known genetic causes of PFBC include loss‐of‐function mutations in genes involved in either of three processes—platelet‐derived growth factor (PDGF) signaling, phosphate homeostasis or protein glycosylation—with unclear molecular links. To provide insight into the...
Paper Details
Title
Astrocyte–microglial association and matrix composition are common events in the natural history of primary familial brain calcification
Published Date
Oct 10, 2019
Journal
Volume
30
Issue
3
Pages
446 - 464
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Notes
History