Vitamin D deficiency is associated with cortical bone loss and fractures in the elderly

The role of vitamin D on bone microarchitecture and fragility is not clear.To investigate whether vitamin D deficiency (25(OH)D <20 ng/mL) increases cortical bone loss and the severity of fractures.Cross-sectional study of 287 elderly women with at least one prevalent low-impact fracture.Biochemistry, X-rays to identify vertebral fractures (VFs) and to confirm non-vertebral fractures (NonVFs), and high-resolution peripheral quantitative computed...