Evaluation of Continuous Tumor-Size–Based End Points as Surrogates for Overall Survival in Randomized Clinical Trials in Metastatic Colorectal Cancer

Volume: 2, Issue: 9, Pages: e1911750 - e1911750
Published: Sep 20, 2019
Abstract

Importance

Tumor measurements can be used to estimate time to nadir and depth of nadir as potential surrogates for overall survival (OS).

Objective

To assess time to nadir and depth of nadir as surrogates for OS in metastatic colorectal cancer.

Design, Setting, and Participants

Pooled analysis of 20 randomized clinical trials within the Aide et Recherche en Cancerologie Digestive database, which contains academic and...
Paper Details
Title
Evaluation of Continuous Tumor-Size–Based End Points as Surrogates for Overall Survival in Randomized Clinical Trials in Metastatic Colorectal Cancer
Published Date
Sep 20, 2019
Volume
2
Issue
9
Pages
e1911750 - e1911750
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