Original paper
CCR2 knockout ameliorates obesity-induced kidney injury through inhibiting oxidative stress and ER stress
Abstract
CCL2/CCR2 signaling is believed to play an important role in kidney diseases. Several studies have demonstrated that blocking of CCR2 has a therapeutic effect on kidney diseases. However, the effects of CCR2 knockout on obesity-induced kidney injury remain unclear. We investigated the therapeutic effects and the mechanism of CCL2/CCR2 signaling in obesity-induced kidney injury. We used C57BL/6-CCR2 wild type and C57BL/6-CCR2 knockout mice:...
Paper Details
Title
CCR2 knockout ameliorates obesity-induced kidney injury through inhibiting oxidative stress and ER stress
Published Date
Sep 9, 2019
Journal
Volume
14
Issue
9
Pages
e0222352 - e0222352
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Notes
History