A new paradigm for delivering personalised care: integrating genetics with surgical interventions in BEST1 mutations

The availability and reduced cost of genotyping has improved gene susceptibility testing and our scientific understanding of disease pathophysiology. Whilst several personalised translational models exist within medical frameworks, genetic-based surgical therapy is a translational application not widely used in surgical specialties. We present a clinical series of five patients with genetically confirmed bestrophinopathy and malignant glaucoma...