Review paper
Nuclear hormone receptors in parasitic Platyhelminths
Abstract
Nuclear receptors (NRs) belong to a large protein superfamily which includes intracellular receptors for secreted hydrophobic signal molecules, such as steroid hormones and thyroid hormones. They regulate development and reproduction in metazoans by binding to the promoter region of their target gene to activate or repress mRNA synthesis. Isolation and characterization of NRs in the parasitic trematode Schistosoma mansoni identified two...
Paper Details
Title
Nuclear hormone receptors in parasitic Platyhelminths
Published Date
Oct 1, 2019
Volume
233
Pages
111218 - 111218
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