Review paper
Death receptor 5 contributes to cardiomyocyte hypertrophy through epidermal growth factor receptor transactivation
Abstract
Cardiomyocyte survival and death contributes to many cardiac diseases. A common mechanism of cardiomyocyte death is through apoptosis however, numerous death receptors (DR) have been virtually unstudied in the context of cardiovascular disease. Previous studies have identified TNF-related apoptosis inducing ligand (TRAIL) and its receptor, DR5, as being altered in a chronic catecholamine administration model of heart failure, and suggest a role...
Paper Details
Title
Death receptor 5 contributes to cardiomyocyte hypertrophy through epidermal growth factor receptor transactivation
Published Date
Nov 1, 2019
Volume
136
Pages
1 - 14
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