Original paper
A genetically encoded fluorescent biosensor for detecting nitroreductase activity in living cancer cells
Abstract
Genetically encoded fluorescent biosensors are particularly promising sensors to examine biochemical processes in a complex cellular context. RNA mimics of GFP are RNA-fluorophore complexes that emit green fluorescence comparable in brightness to fluorescent proteins. The fluorophore is non-fluorescent until it binds with specific RNA. We designed and developed a dual activated fluorescent probe based on RNA mimics of GFP for the detection of an...
Paper Details
Title
A genetically encoded fluorescent biosensor for detecting nitroreductase activity in living cancer cells
Published Date
Dec 1, 2019
Journal
Volume
1088
Pages
131 - 136
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Notes
History