Original paper
Antiinflammatory activity of ANGPTL4 facilitates macrophage polarization to induce cardiac repair
Abstract
Mesenchymal stem cells (MSCs) can suppress pathological inflammation. However, the mechanisms underlying the association between MSCs and inflammation remain unclear. Under coculture conditions with macrophages, MSCs highly expressed angiopoietin-like 4 (ANGPTL4) to blunt the polarization of macrophages toward the proinflammatory phenotype. ANGPTL4-deficient MSCs failed to inhibit the inflammatory macrophage phenotype. In inflammation-related...
Paper Details
Title
Antiinflammatory activity of ANGPTL4 facilitates macrophage polarization to induce cardiac repair
Published Date
Aug 22, 2019
Journal
Volume
4
Issue
16
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Notes
History