Original paper
Nanolipid-Trehalose Conjugates and Nano-Assemblies as Putative Autophagy Inducers
Abstract
The disaccharide trehalose is an autophagy inducer, but its pharmacological application is severely limited by its poor pharmacokinetics properties. Thus, trehalose was coupled via suitable spacers with squalene (in 1:2 and 1:1 stoichiometry) and with betulinic acid (1:2 stoichiometry), in order to yield the corresponding nanolipid-trehalose conjugates 1-Sq-mono, 2-Sq-bis and 3-Be-mono. The conjugates were assembled to produce the corresponding...
Paper Details
Title
Nanolipid-Trehalose Conjugates and Nano-Assemblies as Putative Autophagy Inducers
Published Date
Aug 20, 2019
Journal
Volume
11
Issue
8
Pages
422 - 422
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Notes
History