Sweet Memories of 8 Empowered by Butyrate

Formation of memory T cells is coupled with changes of metabolic status, yet how environmental metabolites affect the transition remains largely unknown. In this issue of Immunity, Bachem et al., 2019Bachem A. Makhlouf C. Binger K.J. de Souza D.P. Tull D. Hochheiser K. Whitney P.G. Fernandez-Ruiz D. Dähling S. Kastenmüller W. et al.Microbiota-derived short-chain fatty acids promote the memory potential of antigen-activated CD8+ T cells.Immunity....