Therapeutic Potential of 47Sc in Comparison to 177Lu and 90Y: Preclinical Investigations
Abstract
Targeted radionuclide therapy with 177Lu- and 90Y-labeled radioconjugates is a clinically-established treatment modality for metastasized cancer. 47Sc is a therapeutic radionuclide that decays with a half-life of 3.35 days and emits medium-energy β−-particles. In this study, 47Sc was investigated, in combination with a DOTA-folate conjugate, and compared to the therapeutic properties of 177Lu-folate and 90Y-folate, respectively. In vitro,...
Paper Details
Title
Therapeutic Potential of 47Sc in Comparison to 177Lu and 90Y: Preclinical Investigations
Published Date
Aug 20, 2019
Journal
Volume
11
Issue
8
Pages
424 - 424
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