Original paper
Stress resilience is promoted by a Zfp189-driven transcriptional network in prefrontal cortex
Abstract
Understanding the transcriptional changes that are engaged in stress resilience may reveal novel antidepressant targets. Here we use gene co-expression analysis of RNA-sequencing data from brains of resilient mice to identify a gene network that is unique to resilience. Zfp189, which encodes a previously unstudied zinc finger protein, is the highest-ranked key driver gene in the network, and overexpression of Zfp189 in prefrontal cortical...
Paper Details
Title
Stress resilience is promoted by a Zfp189-driven transcriptional network in prefrontal cortex
Published Date
Aug 19, 2019
Journal
Volume
22
Issue
9
Pages
1413 - 1423
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Notes
History