Review paper
Therapeutic Targeting of the IGF Axis
Abstract
The insulin like growth factor (IGF) axis plays a fundamental role in normal growth and development, and when deregulated makes an important contribution to disease. Here, we review the functions mediated by ligand-induced IGF axis activation, and discuss the evidence for the involvement of IGF signaling in the pathogenesis of cancer, endocrine disorders including acromegaly, diabetes and thyroid eye disease, skin diseases such as acne and...
Paper Details
Title
Therapeutic Targeting of the IGF Axis
Published Date
Aug 14, 2019
Journal
Volume
8
Issue
8
Pages
895 - 895
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