A multi-recycling amplification-based sensor for label-free and highly sensitive detection of telomerase from cancer cells
Abstract
The development of methods that can detect telomerase with high selectivity and sensitivity is critical for early diagnosis and treatment of telomerase-related cancers. In this regard, we describe in this work the establishment of a telomerase-initiated and nicking endonuclease-assisted cascade recycling signal amplification approach for non-label and highly sensitive fluorescent detection of telomerase from cancer cells. The target telomerase...
Paper Details
Title
A multi-recycling amplification-based sensor for label-free and highly sensitive detection of telomerase from cancer cells
Published Date
Dec 1, 2019
Journal
Volume
1086
Pages
116 - 121
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