Vascular Ehlers-Danlos Syndrome Diagnosed in a Patient Initiating Hemodialysis

Ehlers-Danlos syndrome (EDS) is an inherited connective tissue disorder that is caused by defects in collagen, other extracellular matrix proteins, or associated enzymes. As of 2017, the syndrome comprises 13 subtypes with a significant overlap in features.1 Among them, vascular EDS (vEDS), the most severe subtype in terms of clinical manifestation and mortality, is caused by a mutation of the COL3A1 gene encoding collagen type III alpha 1...