Large-scale neuroanatomical study uncovers 198 gene associations in mouse brain morphogenesis
Abstract
Brain morphogenesis is an important process contributing to higher-order cognition, however our knowledge about its biological basis is largely incomplete. Here we analyze 118 neuroanatomical parameters in 1,566 mutant mouse lines and identify 198 genes whose disruptions yield NeuroAnatomical Phenotypes (NAPs), mostly affecting structures implicated in brain connectivity. Groups of functionally similar NAP genes participate in pathways involving...
Paper Details
Title
Large-scale neuroanatomical study uncovers 198 gene associations in mouse brain morphogenesis
Published Date
Aug 1, 2019
Journal
Volume
10
Issue
1
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