Match!

How words impact on pain.

Published on Aug 1, 2019in Brain and behavior2.072
· DOI :10.1002/BRB3.1377
Alexander Ritter5
Estimated H-index: 5
,
Marcel Franz5
Estimated H-index: 5
(FSU: University of Jena)
+ 1 AuthorsThomas Weiss36
Estimated H-index: 36
(FSU: University of Jena)
Abstract
INTRODUCTION: The wording used before and during painful medical procedures might significantly affect the painfulness and discomfort of the procedures. Two theories might account for these effects: the motivational priming theory (Lang, 1995, American Psychologist, 50, 372) and the theory of neural networks (Hebb, 1949, The organization of behavior. New York, NY: Wiley; Pulvermuller, 1999, Behavioral and Brain Sciences, 22, 253; Pulvermuller and Fadiga, 2010, Nature Reviews Neuroscience, 11, 351). METHODS: Using fMRI, we investigated how negative, pain-related, and neutral words that preceded the application of noxious stimuli as priming stimuli affect the cortical processing and pain ratings of following noxious stimuli. RESULTS: Here, we show that both theories are applicable: Stronger pain and stronger activation were observed in several brain areas in response to noxious stimuli preceded by both, negative and pain-related words, respectively, as compared to preceding neutral words, thus supporting motivational priming theory. Furthermore, pain ratings and activation in somatosensory cortices, primary motor cortex, premotor cortex, thalamus, putamen, and precuneus were even stronger for preceding pain-related than for negative words supporting the theory of neural networks. CONCLUSION: Our results explain the influence of wording on pain perception and might have important consequences for clinical work.
  • References (32)
  • Citations (2)
📖 Papers frequently viewed together
20015.81NeuroImage
1980
78% of Scinapse members use related papers. After signing in, all features are FREE.
References32
Newest
#1Katja Wiech (John Radcliffe Hospital)H-Index: 33
Phenomena such as placebo analgesia or pain relief through distraction highlight the powerful influence cognitive processes and learning mechanisms have on the way we perceive pain. Although contemporary models of pain acknowledge that pain is not a direct readout of nociceptive input, the neuronal processes underlying cognitive modulation are not yet fully understood. Modern concepts of perception—which include computational modeling to quantify the influence of cognitive processes—suggest that...
82 CitationsSource
#1Maria RichterH-Index: 5
Last. Thomas Weiss (FSU: University of Jena)H-Index: 36
view all 8 authors...
BACKGROUND: Negative affective and pain-related cues, such as pictures or words, have been shown to act as primes and enhance the perceived intensity of subsequent painful events. For pain-related semantic primes, it remains unclear whether this effect depends on negative valence itself or, specifically, on the pain-relatedness of the words.
12 CitationsSource
How brain structures and neuronal circuits mechanistically underpin symbolic meaning has recently been elucidated by neuroimaging, neuropsychological, and neurocomputational research. Modality-specific ‘embodied' mechanisms anchored in sensorimotor systems appear to be relevant, as are ‘disembodied' mechanisms in multimodal areas. In this paper, four semantic mechanisms are proposed and spelt out at the level of neuronal circuits: referential semantics, which establishes links between symbols an...
202 CitationsSource
#1Dale J. Barr (Glas.: University of Glasgow)H-Index: 25
#2Roger Levy (UCSD: University of California, San Diego)H-Index: 27
Last. Harry TilyH-Index: 11
view all 4 authors...
Linear mixed-effects models (LMEMs) have become increasingly prominent in psycholinguistics and related areas. However, many researchers do not seem to appreciate how random effects structures affect the generalizability of an analysis. Here, we argue that researchers using LMEMs for confirmatory hypothesis testing should minimally adhere to the standards that have been in place for many decades. Through theoretical arguments and Monte Carlo simulation, we show that LMEMs generalize best when th...
2,829 CitationsSource
#1Rachel L. Moseley (Cognition and Brain Sciences Unit)H-Index: 11
#2Francesca Carota (Cognition and Brain Sciences Unit)H-Index: 5
Last. Friedemann Pulvermüller (FU: Free University of Berlin)H-Index: 72
view all 5 authors...
Sensorimotor areas activate to action- and object-related words, but their role in abstract meaning processing is still debated. Abstract emotion words denoting body internal states are a critical test case because they lack referential links to objects. If actions expressing emotion are crucial for learning correspondences between word forms and emotions, emotion word–evoked activity should emerge in motor brain systems controlling the face and arms, which typically express emotions. To test th...
90 CitationsSource
#1Johannes OttH-Index: 19
#2Stefanie AustH-Index: 15
Last. Regina PrombergerH-Index: 13
view all 4 authors...
Objective:Venous blood sampling is one of the most common diagnostic medical procedures performed in clinical practice. It has been shown that negatively loaded words may result in negative affective reactions and, consequently, in an increased perception of pain. We aimed to evaluate whether common
19 CitationsSource
Purpose of reviewIt is proposed that central rather than peripheral factors may be important in pain chronicity. We review recent empirical findings on these processes and discuss implications for treatment and prevention.Recent findingsThe literature on neuroimaging of pain and on learning processe
55 CitationsSource
#1Judith Eck (FSU: University of Jena)H-Index: 2
#2Maria Richter (FSU: University of Jena)H-Index: 5
Last. Thomas Weiss (FSU: University of Jena)H-Index: 36
view all 5 authors...
Several brain areas that constitute the neural matrix of pain can be activated by noxious stimuli and by pain-relevant cues, such as pictures, facial expressions, and pain-related words. Although chronic pain patients are frequently exposed to pain-related words, it remains unclear whether their pain matrix is specifically activated during the processing of such stimuli in comparison to healthy subjects. To answer this question, we compared the neural activations induced by verbal pain descripto...
47 CitationsSource
#1Friedemann Pulvermüller (Cognition and Brain Sciences Unit)H-Index: 72
#2Luciano Fadiga (IIT: Istituto Italiano di Tecnologia)H-Index: 54
Action and perception are functionally linked in the brain, but a hotly debated question is whether perception and comprehension of stimuli depend on motor circuits. Brain language mechanisms are ideal for addressing this question. Neuroimaging investigations have found specific motor activations when subjects understand speech sounds, word meanings and sentence structures. Moreover, studies involving transcranial magnetic stimulation and patients with lesions affecting inferior frontal regions ...
544 CitationsSource
#1Maria Richter (Schiller International University)H-Index: 5
#2Judith Eck (FSU: University of Jena)H-Index: 2
Last. Thomas Weiss (FSU: University of Jena)H-Index: 36
view all 5 authors...
Previous studies suggested that areas of the pain matrix of the human brain are recruited by the processing of pain-related environmental cues such as pain-related pictures or descriptors of pain. However, it is still sketchy whether those activations are specific to the pain-relevance of the stimuli or simply reflect a general effect of negative valence or increased arousal. The present study investigates the neural mechanisms underlying the processing of pain-related, negative, positive, and n...
66 CitationsSource
Cited By2
Newest
Chronische Schmerzsyndrome nehmen in unserer Gesellschaft zu. Tragen neben lebensstilbedingten Faktoren und gesellschaftlichen Entwicklungen auch Therapeuten und Mediziner dazu bei, dass Schmerzen persistieren? Konnen Physiotherapeuten neben psychosozialen Risikofaktoren selbst zur Yellow Flag werden? Eine Analyse.
Source
Die psychische Verfassung hat einen erheblichen Einfluss darauf, wie jemand Schmerzen wahrnimmt und verarbeitet. Neuere Studien zeigen, dass sich bereits das Lesen oder Horen schmerzbezogener Worter oder negativer Suggestionen auf die Aktivierung der Schmerz-Neuromatrix auswirken. Das hat weitreichende Implikationen fur den Umgang mit Kranken.
Source