Zinc deficits, mucositis, and mucosal macrophage perturbation

Purpose of review Mucositis is a common and therapy-limiting adverse effect of cancer treatments including radiotherapy, chemotherapy, and immunotherapy. The optimal zinc formulation, dosage, and timing of administration warrant further research as does the efficacious prevention of febrile mucositis that predisposes to febrile neutropenia. Recent findings Metaanalyses concluded that zinc sulfate failed to significantly reduce the incidence or...