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Luis Vitetta
University of Sydney
EndocrinologyAlternative medicineDiabetes mellitusMedicineGastroenterology
280Publications
29H-index
2,975Citations
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Publications 272
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The concept of the mind, human thought processes and the physical world is not a novel idea in science. Numerous explanations have been proposed, whether from scientific viewpoints or as for example constructing imaginative visions—notably as depicted by the Creation of Adam ( Figure 1 ), where the mind of man and man’s reflexions are illustrated through Michaelangelo’s sagittal section of the brain that is interestingly similar to modern day anatomical illustrations of the cranium and brain (1)...
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#1Talia Palacios (USYD: University of Sydney)H-Index: 4
#1Talia PalaciosH-Index: 1
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Early treatment may prevent or delay the onset of type 2 diabetes mellitus (T2DM) in individuals who are at high risk. Lifestyle interventions and the hypoglycemic drug metformin have been shown to reduce T2DM incidence. The effectiveness of such interventions may be enhanced by targeting environmental factors such as the intestinal microbiota, which has been proven to predict the response to lifestyle interventions and play a part in mediating the glucose-lowering effects of metformin. Shifts i...
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#1Jiezhong ChenH-Index: 25
#2Avni SaliH-Index: 15
Last. Luis Vitetta (USYD: University of Sydney)H-Index: 29
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Surgical procedures for the symptomatic removal of the gallbladder and the vermiform appendix have been posited to adversely shift the assemblage of the intestinal microbiome increasing the risk of disease. The associated mechanisms have been linked with dysbiosis of the gut microbiota. Cholecystectomy causes changes of bile acid compositions and bile secretion patterns as bile acids interact with the intestinal microbiota in a bidirectional capacity. An appendectomy precludes the further recolo...
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#1Stephen ClarkeH-Index: 55
#2Luis Vitetta (USYD: University of Sydney)H-Index: 29
Last. Sean HallH-Index: 3
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#1Jiezhong ChenH-Index: 25
#2Luis Vitetta (USYD: University of Sydney)H-Index: 29
Primary sclerosing cholangitis (PSC) is characterized by chronic liver inflammation and cholestasis due to intrahepatic and extrahepatic bile duct inflammation and fibrosis. Cholestasis results in accumulation of bile acids in the liver with a concomitant deficit in the intestines. Accumulation of bile acids could be causal for inflammation of the liver, whereas deficiency of bile acids in the intestines could result in insufficient deoxycholic acid (DCA) in both the intestines and the liver, le...
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#1Luis Vitetta (USYD: University of Sydney)H-Index: 29
#2Belinda Butcher (UNSW: University of New South Wales)H-Index: 6
Last. Elizabeth Steels (USYD: University of Sydney)H-Index: 5
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Background: Herbal medicines present attractive options to patients with chronic diseases. Undertaking clinical studies with patients presenting with symptomless pre-T2D can lead to significant limitations. Methods: A 12-week randomized double-blind placebo-controlled clinical study was conducted that investigated the safety and efficacy of an herbal formulation administered orally for the treatment of pre-type 2 diabetes (pre-T2D). Results: A numerically greater proportion of subjects in the in...
1 CitationsSource
#1Jiezhong ChenH-Index: 25
Last. Luis Vitetta (USYD: University of Sydney)H-Index: 29
view all 2 authors...
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#1Jiezhong ChenH-Index: 25
Last. Luis Vitetta (USYD: University of Sydney)H-Index: 29
view all 2 authors...
: An excessive hyperinflammatory response-caused septic shock is a major medical problem that is associated with pathogenic bacterial infections leading to high mortality rates. The intestinal microbiota and the associated elaborated metabolites such as short chain fatty acid butyrate have been shown to relieve pathogenic bacterial-caused acute inflammation. Butyrate can down-regulate inflammation by inhibiting the growth of pathobionts, increasing mucosal barrier integrity, encouraging obligate...
2 CitationsSource
#1Jiezhong ChenH-Index: 25
#2Luis Vitetta (USYD: University of Sydney)H-Index: 29
: The intestinal microbiota has been reported to affect depression, a common mental condition with severe health-related consequences. However, what mediates the effect of the intestinal microbiota on depression has not been well elucidated. We summarize the roles of the mitochondria in eliciting beneficial effects on the gut microbiota to ameliorate symptoms of depression. It is well known that mitochondria play a key role in depression. An important pathogenic factor, namely inflammatory respo...
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#1Jiezhong ChenH-Index: 25
#2Luis Vitetta (USYD: University of Sydney)H-Index: 29
view all 2 authors...
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