Diagnosis and Treatment of Carbapenemase-Producing Organisms—an Update

Carbapenem-producing organisms (CPO) have become important clinical pathogens in nosocomial infections causing increases in hospital stay, mortality, and costs. We sought to summarize recent findings related to the commonly encountered types of carbapenemases and their detection and review recent findings related to therapeutic options. Many new rapid and reliable methods of identifying carbapenem resistance have become available, underscoring...