B/O plasmid R16 from 1956 carries an In1-like class 1 integron embedded in a complex region containing parts of the Acinetobacter baumannii AbaR resistance island

The IncB/O multiresistance plasmid R16, recovered in 1956 and used in experimental studies of B/O plasmid features, was sequenced. The resistance genes are all within a class 1 integron closely related to In1 containing the cassette array oxa2 - aadA1 - oxa2 -orfD and the sul1 gene in the 3′-conserved segment (3′-CS), with Tn 10 , containing tetA (B), inserted just inside the 3′-CS. The integron is part of a 25,144 bp region inserted in the...