Distinct roles of striatal direct and indirect pathways in value-based decision making
Abstract
The striatum is critically involved in value-based decision making. However, it is unclear how striatal direct and indirect pathways work together to make optimal choices in a dynamic and uncertain environment. Here, we examined the effects of selectively inactivating D1 receptor (D1R)- or D2 receptor (D2R)-expressing dorsal striatal neurons (corresponding to direct- and indirect-pathway neurons, respectively) on mouse choice behavior in a...
Paper Details
Title
Distinct roles of striatal direct and indirect pathways in value-based decision making
Published Date
Jul 16, 2019
Journal
Volume
8
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