Structural characterization of life-extending Caenorhabditis elegans Lipid Binding Protein 8
Abstract
The lysosome plays a crucial role in the regulation of longevity. Lysosomal degradation is tightly coupled with autophagy that is induced by many longevity paradigms and required for lifespan extension. The lysosome also serves as a hub for signal transduction and regulates longevity via affecting nuclear transcription. One lysosome-to-nucleus retrograde signaling pathway is mediated by a lysosome-associated fatty acid binding protein LBP-8 in...
Paper Details
Title
Structural characterization of life-extending Caenorhabditis elegans Lipid Binding Protein 8
Published Date
Jul 10, 2019
Journal
Volume
9
Issue
1
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History