Blood ceramides as novel markers for renal impairment in systemic lupus erythematosus

Lupus nephritis (LN) is the most common organ manifestation in systemic lupus erythematosus (SLE) and associated with a poor prognosis. Still, a noninvasive but reliable method to diagnose LN has not been established. Thus, we evaluated whether blood sphingolipids could serve as valid biomarkers for renal injury.In this cross-sectional study, 82 participants were divided into three groups: 36 healthy controls and 17 SLE patients without renal...