Match!

Association of optic nerve sheath diameter in ocular ultrasound with prognosis in patients presenting with acute stroke symptoms

Published on Oct 1, 2019in Turkish journal of emergency medicine
· DOI :10.1016/j.tjem.2019.07.001
Javad Seyedhosseini3
Estimated H-index: 3
(Tehran University of Medical Sciences),
Mehrad Aghili (Tehran University of Medical Sciences)+ 1 AuthorsFarzaneh Shirani3
Estimated H-index: 3
(Tehran University of Medical Sciences)
Abstract
Abstract Background Measurement of optic nerve sheath diameter (ONSD) by means of ocular ultrasound (US), can diagnose elevated intracranial pressure (ICP). Stroke accompanied by elevated ICP might have a worse prognosis. Objective To determine the relationship of ONSD in ocular US with prognosis in acute stroke in the emergency department (ED). Methods Patients with acute presentations of stroke, presenting to the ED in 2017 (during six months), were enrolled in our study. US exam was performed on all of them and ONSD was determined in two longitudinal and transverse dimensions. Demographic data, rate of patients' admission in the ward or intensive care unit, one-month patients’ outcome and type of stroke were recorded. The relationship of mean ONSD was evaluated with study variables. Results In this study, 60 patients were enrolled. The mean ± SD ONSD in the deceased cases was 4.40 ± 0.64 mm and in the survived patients was 3.83 ± 0.56 mm. Youden index calculated ONSD>3.9 mm as the best cut-off point in mortality prognosis. It has a sensitivity of 83.3% and a specificity of 59.2%. Conclusions Increased ONSD had a direct relationship with mortality rate in acute stroke.
  • References (20)
  • Citations (0)
📖 Papers frequently viewed together
1 Citations
4 Authors (A.K. Thotakura, ..., R.R. Mareddy)
3 Citations
78% of Scinapse members use related papers. After signing in, all features are FREE.
References20
Newest
Abstract Background ONSD (optic nerve sheath diameter) is a method used for indirect measurement of the increased intracranial pressure. In previous studies, the relation between the increased intracranial pressure and ONSD was analyzed in the patients suffering from cerebrovascular diseases (CVD). In our study, the patients suffering from ischemic CVD were categorized into 4 subgroups according to Oxfordshire Community Stroke Project classification (OCSP); the relationship between each group an...
4 CitationsSource
#1Patrick Goeres (UM: University of Manitoba)H-Index: 2
#2Frederick A. Zeiler (UM: University of Manitoba)H-Index: 13
Last. Lawrence M. Gillman (UM: University of Manitoba)H-Index: 14
view all 5 authors...
Abstract Background Ultrasound assessment of optic nerve sheath diameter (ONSD) has been suggested as a non-invasive measure of intracranial pressure. Numerous small studies suggest its validity; however, discrepancy exists around normal values for ONSD. In this study we sought to define a normal value range for ONSD in a population of healthy adult volunteers. Methods ONSD was measured in healthy adult volunteers and a normal range was defined using descriptive statistics. A regression analysis...
18 CitationsSource
#1Piergiorgio LochnerH-Index: 15
#2Maurizio Leone (Casa Sollievo della Sofferenza)H-Index: 43
Last. Francesco Brigo (University of Verona)H-Index: 23
view all 7 authors...
Abstract Objective In patients with acute optic neuritis (AON) transorbital sonography may reveal a thickening of the retrobulbar portion of the optic nerve. Our aim was to systematically review the diagnostic accuracy of ultrasonography of optic nerve diameter (OND) for assessment of AON. Methods MEDLINE, EMBASE (1966–October 2014) was searched to identify studies reporting data on patients with AON (with/without multiple sclerosis) assessed by B-mode transorbital ultrasonography. Thereafter, t...
12 CitationsSource
Background and Aims: Analysis to correlate the measurements of optic nerve sheath diameter (ONSD) obtained by using ultrasound to magnetic resonance imaging (MRI) techniques in order to establish the accuracy of ocular sonography as a noninvasive modality for detecting raised intracranial pressure (ICP). Materials and Methods: A prospective, observational study was performed in 100 cases of adult meningoencephalitis patients admitted to Intensive Care Unit in whom MRI was performed for neurodiag...
8 CitationsSource
#1Han Y.H. Chen (Fujian Medical University)H-Index: 2
#2Gui-Sheng Ding (Fujian Medical University)H-Index: 1
Last. Jian-Xin Zhou (Capital Medical University)H-Index: 3
view all 5 authors...
Background: Measurement of optic nerve sheath diameter (ONSD) is a fast and non-invasive method in detecting elevated intracranial pressure. However, the reported normal range of ONSD was inconsistent. The objective of the study was to determine the normal range of ONSD in healthy Chinese adults. Methods: Eyeball transverse diameter (ETD), optic nerve diameter (OND), and ONSD were measured by ultrasound examination in healthy adult volunteers. The OND and ONSD were assessed 3 mm behind the globe...
15 CitationsSource
#1Christopher Hawthorne (Glas.: University of Glasgow)H-Index: 2
#2Ian Piper (Southern General Hospital)H-Index: 23
Since Monro published his observations on the nature of the contents of the intracranial space in 1783 there has been investigation of the unique relationship between the contents of the skull and the intracranial pressure (ICP). This is particularly true following traumatic brain injury (TBI), where it is clear that elevated ICP due to the underlying pathological processes is associated with a poorer clinical outcome. Consequently, there is considerable interest in monitoring and manipulating I...
42 CitationsSource
#1Rapeephan R. MaudeH-Index: 9
#2Amir Hossain (Chittagong Medical College Hospital)H-Index: 12
Last. Richard J. Maude (University of Oxford)H-Index: 25
view all 12 authors...
Introduction Measurement of optic nerve sheath diameter (ONSD) by ultrasound is increasingly used as a marker to detect raised intracranial pressure (ICP). ONSD varies with age and there is no clear consensus between studies for an upper limit of normal. Knowledge of normal ONSD in a healthy population is essential to interpret this measurement. Methods In a prospective observational study, ONSD was measured using a 15 MHz ultrasound probe in healthy volunteers in Chittagong, Bangladesh. The aim...
25 CitationsSource
#1Edward C. JauchH-Index: 58
#2Jeffrey L. SaverH-Index: 103
Last. Howard YonasH-Index: 59
view all 15 authors...
Background and Purpose—The authors present an overview of the current evidence and management recommendations for evaluation and treatment of adults with acute ischemic stroke. The intended audienc...
3,310 CitationsSource
#1Jochen BäuerleH-Index: 5
#2Piergiorgio LochnerH-Index: 15
Last. Max NedelmannH-Index: 18
view all 4 authors...
BACKGROUND The use of an ultrasound-based evaluation of the optic nerve sheath diameter (ONSD) has previously been demonstrated for detecting raised intracranial pressure. In order to be feasible in clinical workup, the test qualities of transorbital ultrasonography need to be determined. The aim of this study was therefore to establish normal values and to assess the intra- and interobserver reliability of this method. METHODS Using a 9-3 MHz linear array transducer, the ONSD of 40 healthy subj...
94 CitationsSource
Background:Management strategies after severe traumatic brain injury (TBI) target prevention and treatment of intracranial hypertension (ICH) and cerebral hypoperfusion (CH). We have previously established that continuous automated recordings of vital signs (VS) are more highly correlated with outco
70 CitationsSource
Cited By0
Newest