Association of optic nerve sheath diameter in ocular ultrasound with prognosis in patients presenting with acute stroke symptoms

Published on Oct 1, 2019in Turkish journal of emergency medicine
· DOI :10.1016/j.tjem.2019.07.001
Javad Seyedhosseini3
Estimated H-index: 3
(Tehran University of Medical Sciences),
Mehrad Aghili (Tehran University of Medical Sciences)+ 1 AuthorsFarzaneh Shirani3
Estimated H-index: 3
(Tehran University of Medical Sciences)
Abstract Background Measurement of optic nerve sheath diameter (ONSD) by means of ocular ultrasound (US), can diagnose elevated intracranial pressure (ICP). Stroke accompanied by elevated ICP might have a worse prognosis. Objective To determine the relationship of ONSD in ocular US with prognosis in acute stroke in the emergency department (ED). Methods Patients with acute presentations of stroke, presenting to the ED in 2017 (during six months), were enrolled in our study. US exam was performed on all of them and ONSD was determined in two longitudinal and transverse dimensions. Demographic data, rate of patients' admission in the ward or intensive care unit, one-month patients’ outcome and type of stroke were recorded. The relationship of mean ONSD was evaluated with study variables. Results In this study, 60 patients were enrolled. The mean ± SD ONSD in the deceased cases was 4.40 ± 0.64 mm and in the survived patients was 3.83 ± 0.56 mm. Youden index calculated ONSD>3.9 mm as the best cut-off point in mortality prognosis. It has a sensitivity of 83.3% and a specificity of 59.2%. Conclusions Increased ONSD had a direct relationship with mortality rate in acute stroke.
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