Definitions, adjudication, and reporting of pulmonary embolism–related death in clinical studies: A systematic review

BackgroundPulmonary embolism (PE)–related death is a component of the primary outcome in many venous thromboembolism (VTE) studies. The absence of a standardized definition for PE‐related death hampers study outcome evaluation and between‐study comparisons.ObjectivesTo summarize definitions for PE‐related death used in recent VTE studies and to assess the PE‐related death rate.Patients/MethodsA systematic literature search was conducted on 26...