Decentralized care with generic direct-acting antivirals in the management of chronic hepatitis C in a public health care setting

•The goal of the ‘Punjab Model’ is HCV Elimination by 2030, using primary care providers and remote treatment monitoring. •We enrolled 48,088 people (14.8% with compensated cirrhosis; 69.9% with genotype 3). •SVR12 was achieved in 91.6%, 67.6% and 91.2%, per protocol, intention-to-treat (ITT) and a modified ITT, respectively. •Decentralized care of hepatitis C with direct-acting antiviral - regimens is safe and effective, regardless of genotype...