Oligodendrocyte precursors gain Schwann cell‐like phenotype and remyelinate axons upon engraftment into peripheral nerves

Volume: 13, Issue: 10, Pages: 1854 - 1860
Published: Jul 30, 2019
Abstract
The ability to treat large peripheral nerve injuries may be greatly advanced if an accessible source of human myelinating cells is identified, as it overcomes one of the major limitations of acellular or synthetic nerve guides compared with autografts, the gold standard for large defect repair. Methods to derive oligodendrocyte precursor cells (OPCs) from human pluripotent stem cells have advanced to the point where they have been shown capable...
Paper Details
Title
Oligodendrocyte precursors gain Schwann cell‐like phenotype and remyelinate axons upon engraftment into peripheral nerves
Published Date
Jul 30, 2019
Volume
13
Issue
10
Pages
1854 - 1860
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