Journal of Tissue Engineering and Regenerative Medicine
Papers 2189
1 page of 219 pages (2,189 results)
#1Salima Nedjari (Empa: Swiss Federal Laboratories for Materials Science and Technology)H-Index: 1
#2Firas AwajaH-Index: 19
Last. George Altankov (BAS: Bulgarian Academy of Sciences)H-Index: 23
view all 5 authors...
Mimicking the complex organization of the extracellular matrix (ECM), especially structure and dimensionality, is necessary to produce living tissues from stem cells. In compliance with a previously-established role of nanofiber organization for the osteogenic differentiation of stem cells, here we used hybrid fibrinogen/poly(L-lactide-e-caprolactone) (FBG/PLCL) nanofibers arranged in aligned and honeycomb configuration to recapitulate the highly oriented ECM of the cortical bone and the sponge-...
#1Jitsuro Tsukada (Nihon University)H-Index: 4
#2Frederic Wolf (RWTH Aachen University)H-Index: 6
Last. Masahiro Jinzaki (Keio: Keio University)H-Index: 31
view all 12 authors...
PURPOSE We propose in vitro endothelialization of drug-eluting stents (DES) to overcome late stent thrombosis by directly introducing late-outgrowth human endothelial progenitor cells (EPCs) at the target site utilizing abluminal DES. MATERIALS AND METHODS Isolated EPCs were confirmed as late-outgrowth EPCs by flow cytometric analysis. Abluminally paclitaxel-loaded stents were seeded with different cell concentrations and durations to determine optimal seeding conditions, in both uncrimped and c...
#1Zhi-Qing Liu (SJTU: Shanghai Jiao Tong University)H-Index: 2
#2Yu-Wei Ge (SJTU: Shanghai Jiao Tong University)H-Index: 2
Last. Jie Zhao (SJTU: Shanghai Jiao Tong University)H-Index: 6
view all 11 authors...
The repair of large bone defects has always been a challenge, especially with respect to regeneration capacity and autogenous bone availability. To address this problem, we fabricated a 3D-printed polylactic acid (PLA) and hydroxyapatite (HA) scaffold (3D-printed PLA-HA, providing scaffold) loaded with enhanced bone marrow (eBM, providing seed cells) combined with induced membrane (IM, providing grow factors) to repair large radial defects in rabbits. In vitro assays, we demonstrated that 3D-pri...
BACKGROUND Skin ulcers are non-healed wounds caused inflammation of epidermis up to the dermis, which is significantly reducing the quality of life due to it is causing pain and limiting the body movements. Amniotic membrane (AM) is a placental collagenous biomaterial which featured with many biological and mechanical properties important for tissue engineering and regenerative medicine. AIM OF WORK Evaluate the efficacy of topical antibiotic washing followed with irradiated human amniotic membr...
#1Ian Woods (UCD: University College Dublin)H-Index: 1
#2Alexander Black (National University of Ireland, Galway)H-Index: 11
Last. Thomas C. Flanagan (UCD: University College Dublin)H-Index: 17
view all 5 authors...
The development of tissue-engineered vascular grafts (TEVGs) for pediatric applications must consider unique factors associated with this patient cohort. While the increased elastogenic potential of neonatal cells offers an opportunity to overcome the long-standing challenge of in vitro elastogenesis, neonatal patients have a lower tolerance for autologous tissue harvest and require grafts that exhibit growth potential. The purpose of this study was to apply a multi-pronged strategy to promote e...
The shortage of donor corneas as well as the limitations of tissue substitutes leads to the necessity to develop alternative materials for ocular surface reconstruction. Corneal surface substitutes must fulfill specific requirements such as high transparency, low immunogenicity, and mechanical stability combined with elasticity. This in vitro study evaluates a decellularized matrix secreted from human corneal fibroblast (hCF) as an alternative material for ocular surface reconstruction. HCF from...
AIM To describe the treatment of an infected segmental bone defect in a cat using a novel, custom-designed titanium implant seeded with adipose-derived stem cells (AdMSCs) to facilitate osseous ingrowth and preserve limb function. CASE REPORT Large bone defects occur secondary to trauma, infection, or neoplasia, and often result in amputation. We established a novel autologous AdMSC-impregnated trabecular metal spacer made using 3D printing, to bridge the distal tibia and metatarsal bones in the...
#1Ethan Matz (Wake Forest Institute for Regenerative Medicine)H-Index: 3
#2Parth Thakker (Wake Forest Institute for Regenerative Medicine)
Last. James J. Yoo (Wake Forest Institute for Regenerative Medicine)H-Index: 69
view all 12 authors...
INTRODUCTION Human placental stem cells (PSC) enhance histological and functional recovery in a rodent erectile dysfunction (ED) model. We tested the hypothesis that bioactive factors secreted by PSC (i.e. the secretome) mediate functional recovery and that acellular conditioned media from PSC culture (PSC-CM) could be used independently to facilitate functional and histological recovery. METHODS To identify factors relative to efficacy of PSC, a comparison of CM from PSC and three additional hu...
#1Klara Janjić (Medical University of Vienna)H-Index: 7
#2Barbara Schädl (Medical University of Vienna)H-Index: 2
Last. Hermann Agis (Medical University of Vienna)H-Index: 14
view all 4 authors...
Collagen membranes and bone substitute are popular biomaterials in guided tissue regeneration for treatment of traumatized or diseased periodontal tissue. Development of these biomaterials starts in monolayer cell culture, failing to reflect in vivo tissue organization. Spheroid cultures potentially mimic in vivo tissues in structure and functionality. This study aims to compare GC monolayers and spheroids to ex vivo gingiva. Human GC monolayers, spheroids and gingiva ex vivo tissues were cultur...
#1Daichi Takizawa (Tokai University)H-Index: 1
#2Masato Sato (Tokai University)H-Index: 27
Last. Masahiko Watanabe (Tokai University)H-Index: 16
view all 9 authors...
Although cell transplantation has attracted much attention in regenerative medicine, animal models continue to be used in translational research to evaluate safety and efficacy because cell sources and transplantation modalities are so diverse. In the present study, we investigated the regenerative effects of human chondrocyte sheets on articular cartilage in a xenogeneic transplantation model using immune-deficient rats. Osteochondral defects were created in the knee joints of immune-deficient ...
Top fields of study
Biomedical engineering
Mesenchymal stem cell
Tissue engineering