Validation, clinical utility and limitations of the Amsterdam-Oxford model for primary sclerosing cholangitis

•Reliable estimates of survival are pivotal to optimize clinical management of patients with PSC. •The Amsterdam-Oxford model (AOM) was recently introduced to estimate survival for patients with PSC at diagnosis. •The AOM has adequate discriminatory performance and good predictive accuracy at PSC diagnosis. •It maintains this performance and accuracy at other time points during follow-up. Background & Aims Recently the Amsterdam-Oxford model...